| Date | Home | Away | Result |
|---|---|---|---|
| 28/10/25 17:30 | US Lecce | SSC Napoli | 0-1 |
| 28/10/25 19:45 | Atalanta Bergamo | AC Milan | 1-1 |
| 29/10/25 17:30 | Como Calcio | Hellas Verona | --- |
| 29/10/25 17:30 | Juventus Turin | Udinese Calcio | --- |
| 29/10/25 17:30 | AS Roma | Parma Calcio 1913 | --- |
| 29/10/25 19:45 | FC Bologna | FC Turin | --- |
| 29/10/25 19:45 | Inter Milan | Fiorentina | --- |
| 29/10/25 19:45 | Genua CFC | US Cremonese | --- |
| 30/10/25 17:30 | Cagliari Calcio | Sassuolo Calcio | --- |
| 30/10/25 19:45 | Pisa Sporting Club | Lazio Rom | --- |